There are multiple types of rooms available at Hampton Inn Knoxville-East. These include King Room - Non-Smoking, Non-Smoking King Study, Queen Room with Two Queen Beds/Disability Access with Tub - Non-Smoking, Queen Room with Two Queen Beds - Non-Smoking, and King Room with Roll-In Shower - Disability/Hearing Accessible - Non-Smoking. The rooms can accommodate varying numbers of adults and children, ranging from 3 adults and 2 children to 6 adults and 4 children. Smoking is not allowed in any of the rooms. The bed sizes range from King size to Queen size, with some rooms also having a sofa bed.

Guests at the Hampton Inn Knoxville-East can enjoy their time at the hotel by taking advantage of the leisure amenities provided. The hotel features both an indoor and outdoor swimming pool, allowing guests to relax and cool off at any time of the year. Whether they prefer a refreshing swim indoors or a sun-soaked poolside experience outdoors, guests have the option to choose their preferred pool setting.

In addition to the pools, the hotel also offers a fitness center for guests who want to stay active during their stay. The fitness center provides various equipment and facilities for guests to work out and maintain their fitness routines.

For those looking for some indoor entertainment, the hotel also offers board games and puzzles, providing guests with a fun and engaging way to pass the time.