Hyatt Regency - Greenville is a 3-star hotel in Greenville, South Carolina, United States. Located just 0.2mi from the city center, the property sits at 220 North Main Street.

Featured amenities include free Wi-Fi, a free fitness center, and an outdoor swimming pool, along with an on-site restaurant and a free business center. A 24-hour front desk, non-smoking rooms, air conditioning, a terrace, sun deck, and views contribute to comfort, while free toiletries and a bathtub add to convenience. Parking on site and pet-friendly options are available for an extra charge.

With 477 reviews, this hotel makes a notable impression in Greenville's hospitality scene. Minimum price starts from $156.

Greenville’s Hyatt Regency greets travelers with a vibe that blends city energy with easy comfort. The seasonal outdoor pool offers an adults-only escape, while the terrace and sun deck provide fresh vantage points over downtown. An on-site restaurant serves American cuisine in settings that range from FamilyFriendly to Traditional and Modern, and practical perks like free Wi-Fi, a 24-hour front desk, non-smoking rooms, and air conditioning keep evenings smooth after bright-day adventures.

Accommodations span a diverse range, from practical Dormitory Standard and Single Room to more generous options like King Room with Street View (452 sqft), Room - 2 Queen (344 sqft), and Deluxe (about 355 sqft). Larger options include suites such as Panoramic View (624 sqft) and Atrium View (1001 sqft), offering different layouts and views to suit solo travelers, couples, or groups seeking extra space.

Pet-friendly policy welcomes animals on request with possible charges, and on-site parking keeps arrival and departures convenient. Dining is easy with the on-site Hotel Restaurant, delivering American fare in a mix of ambiances—FamilyFriendly, Traditional, and Modern. Payment flexibility is built in, with major cards accepted (cash is not accepted), making transactions seamless after a day of Greenville exploration.