Welcome to the 21c Museum Hotel Lexington, where art, luxury, and sophistication meet in the heart of Lexington-Fayette, Kentucky. This 4-star hotel is located at 167 West Main Street, just 2.1mi from the vibrant city center. With 311 reviews, this hotel is highly recommended by previous guests for its exceptional service and top-notch amenities.

Your stay at the 21c Museum Hotel Lexington starts from $151 per night, offering excellent value for a memorable experience. The hotel provides a range of amenities to ensure your comfort and convenience, including a fitness center, free Wi-Fi, and a 24-hour front desk. Indulge in delicious meals at the onsite restaurant, or enjoy a refreshing drink at the bar. For those traveling with little ones, kids' meals are available. Business travelers will appreciate the free business center and access to healthcare professionals.

Immerse yourself in the artistic ambiance of the hotel as it showcases temporary art galleries, offering a unique cultural experience during your stay. Enjoy complimentary walking tours and classes about local culture, all while surrounded by captivating artwork. The 21c Museum Hotel Lexington combines luxury accommodations with an art-filled experience, making it the ideal choice for travelers seeking a truly unforgettable stay.

When you stay at the 21c Museum Hotel Lexington, you not only get to indulge in luxurious accommodations and exceptional service, but you also have the opportunity to immerse yourself in the vibrant art scene. With temporary art galleries showcasing captivating artwork, this hotel truly offers a unique cultural experience. As you wander through the hallways adorned with thought-provoking pieces, you'll feel inspired and invigorated, creating lasting memories during your stay.

For those seeking a gastronomic adventure, Lockbox, the onsite restaurant at the 21c Museum Hotel Lexington, is a must-visit. Offering a fusion of American and local cuisines, Lockbox promises a delightful culinary experience that will tantalize your taste buds. Whether you're in the mood for a hearty meal or a light snack, Lockbox has something for every palate. Pair your meal with a refreshing drink from the bar, and you'll have everything you need for a fantastic dining experience right at your doorstep.

To make your stay as stress-free as possible, the 21c Museum Hotel Lexington accepts various payment methods, including Visa, American Express, Discover, and Mastercard. However, cash is not accepted, so make sure to bring your preferred credit card along for a hassle-free check-in and check-out process. With the convenience of multiple payment options, you can focus on enjoying your stay without any financial worries.