The hotel offers a variety of room types including Family Rooms, Two Bedroom Family Rooms, Compact Rooms, TwinDouble Rooms, and Triple Rooms. Smoking is not allowed in any of the rooms. The room sizes range from 194 sqft to 377 sqft. The occupancy of the rooms varies, accommodating anywhere from 2 adults and 1 child to 4 adults and 3 children. The bed configurations include Double beds, Twin beds, and Sofa beds. Some rooms also have a side sea view or sea view.

At Mouikis Hotel Kefalonia, guests can spend their time indulging in a variety of leisure activities. The hotel offers a hot tub/Jacuzzi for relaxation and beach umbrellas and chairs/loungers for those looking to soak up the sun.

Fitness enthusiasts can maintain their exercise routine at the hotel's well-equipped fitness center. For those seeking a tranquil escape, the sun deck provides a peaceful environment to unwind and enjoy the beautiful surroundings.

Guests can also make use of the business center for any work-related needs.

In addition, the hotel offers an array of outdoor activities such as bicycle rental, bike tours, snorkeling, horseback riding, diving, cycling, hiking, canoeing, windsurfing, and fishing.

For guests looking to treat themselves, the spa facilities provide a range of treatments including full-body, head, foot, neck, and back massages, as well as pedicures, manicures, hair treatments, makeup services, and facial treatments.

Lastly, guests can engage in some friendly competition with board games and puzzles provided by the hotel.